Marina Green Dr
"Great view of Alcatraz Island"
Marina Green Drive is a small street off of Marina Blvd. It serves as a tourist spot, having ample parking on both sides of the street. You have a spectacular view of San Francisco bay, Alcatraz Island, and on a clear day you can just barely make out the Golden Gate Bridge. Marina Green is right behind it, although it's nothing more then a huge open grassy area. There isn't really anywhere to sit on the green, as far as benches or picnic tables, but there are benches to sit on near the shore line. It's a little tricky to get to, but if you can find the entrance on Marina Blvd, it's a nice place to sit and relax.
Marine Dr
"Great view of the Golden Gate Bridge"
Marine Drive is a little known side street that leads directly to Ft. Point Historic Site. This is also home to arguably the best view of the Golden Gate bridge, and the location most famous pictures of the bridge were taken from. There is parking off the side of the street to viewing, and also for Ft. Point. It's also surrounded by some beautiful natural scenery. If you want to take a good look at the bridge, or visit Ft. Point, you'll have to travel down Marine Drive. Just beware though, traffic can get a bit congested during the peak tourist season.
Great Hwy
"The easiest route to Lake Merced, but nowhere else.."
Of course, if Lake Merced is your destination, that wont be an issue. If however, you find yourself having another destination, suck it up, and enjoy the scenery....you'll be looking at it for a while. Once you get on great Highway, there are limited (and I really mean limited) exit points to get back off. This highway is a was made as a direct route between the north and south sides of San Fran, and it serves it's purpose well. It will also bring you to Golden Gate Park, and Ocean Beach, but if direct non-interrupted (except for a few traffic lights) travel isn't your cup of tea, you might want to take the side streets, which allow you to venture off the beaten path. Although you do get a spectacular view of the ocean, and photogenic sunset opportunities if you go at the right time.
Point Lobos Ave
"Great for walking, not so much for driving."
Point Lobos Ave is a relatively secluded street overlooking Ocean Beach, Seal Rocks, and also goes past Lincoln Park. And while the traffic usually isn't bad, it much better to walk along the "boardwalk" sidewalk. Doing so will really let you take in the scenery, and avoid the awkward street-side parking jams. The aforementioned scenery is well worth it though, so if you're up for a little exercise and a bit of a lengthy walk, this is one place you should definitely leave the gas guzzler behind for.
John F Kennedy Dr
"One of Golden Gate Parks "Main Veins""
JFK Drive is one of the main routes through Golden Gate Park. There is plenty to see and do around here, but expect the traffic to be high during the summer time when the tourists come out of the wood work. One of my favorite things in the park is the Japanese Tea Garden. The Garden is quiet possibly one of the most relaxing atmospheres I've even experienced. I would definitely recommend dropping by there if you visit Golden Gate Park.
ell Camino del Mar
"Great Views of China Beach, If you can find a spot to look."
If you're lucky enough to be travelling on Lincoln during a day when commuters aren't racing to get to or from work, it offers one of the best views of China Beach, and the Golden Gate Bridge. There is an unofficial rest area by Battery Crossby Rd, and you can usually park your car there for a bit to take a few snapshots.
Presidio Blvd
"One of my favorite scenic routes in CA"
There isn't anything to not like about Presidio Blvd. It's quiet, very scenic. Tranquil in it's own way. One of the few spots in San Francisco where you can let your hair down and just enjoy the endless trees. It kind of had the feel of being lost in the Oregon Pines, but less secluded from civilization. Even though, it's still a great break from the hussle and bussle of the city. Only problem is it doesn't last very long..
Greenwich St
"Quiet & Friendly (For CA Standards That is)"
Greenwich Street is San Fran's version of pleasantville. It's a mostly quiet, friendly neighborhood. Mainly residential, however if that gives way to businesses the further east you travel. If you find yourself passing through Greenwich street, you'll want to stop at the Balboa Cafe or the City Tavern. There are numerous hotels on the strip, and a decent park at the end. Overall it's a nice area close to the beach and some tourist spots.
West 42nd St
"One of the better tourism areas in NYC."
W. 42nd is without a doubt one of NY's tourist hotspots. Littered with Off-Broadway Theatres, you'll be sure to catch a show you'll love. There is also Madame Tussaud's Wax Museum, which features a wonderful Ripley's Believe it or Not Exhibit. And of course don't forget, Times Suare is just past the Hilton Theatre. There is also an HSBC and Chase branch (and I believe a Wachovia if I remember correctly) within a few blocks of Bryant Park. And if you follow 42nd all the way down (towards Jersey) you'll hit the river tour boat piers.